Neuroscientists uncover sensory switches controlling infanticide and parental behaviour in mice

Multisensory Logic of Infant-Directed Aggression by Males. Yoh Isogai et al. Cell, Volume 175, issue 7, p1827-1841.e17, December 13, 2018. https://doi.org/10.1016/j.cell.2018.11.032

Highlights
    •    Reconstituted pup shape and chemosignals trigger aggression by virgin males
    •    Repertoire of seven VNO receptors activated by pups is also stimulated by adult cues
    •    Deletion of receptors to salivary protein and hemoglobin shows role in pup attack
    •    Complex recognition involves pup’s shape and chemosignals from infants and parents

Summary: Newborn mice emit signals that promote parenting from mothers and fathers but trigger aggressive responses from virgin males. Although pup-directed attacks by males require vomeronasal function, the specific infant cues that elicit this behavior are unknown. We developed a behavioral paradigm based on reconstituted pup cues and showed that discrete infant morphological features combined with salivary chemosignals elicit robust male aggression. Seven vomeronasal receptors were identified based on infant-mediated activity, and the involvement of two receptors, Vmn2r65 and Vmn2r88, in infant-directed aggression was demonstrated by genetic deletion. Using the activation of these receptors as readouts for biochemical fractionation, we isolated two pheromonal compounds, the submandibular gland protein C and hemoglobins. Unexpectedly, none of the identified vomeronasal receptors and associated cues were specific to pups. Thus, infant-mediated aggression by virgin males relies on the recognition of pup’s physical traits in addition to parental and infant chemical cues.


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Neuroscientists uncover sensory switches controlling infanticide and parental behaviour in mice
https://www.ucl.ac.uk/swc/sainsbury-wt-news-pub/neuroscientists-uncover-sensory-switches-controlling-infanticide-and-parental-behaviour-in-mice

Both conservatives & liberals resist & accept societal changes, depending on the extent to which they approve or disapprove of the status quo on a given issue; we challenge assumptions on general, context‐independent psychological differences underlying ideologies

Liberalism and Conservatism, for a Change! Rethinking the Association Between Political Orientation and Relation to Societal Change. Jutta Proch, Julia Elad‐Strenger, Thomas Kessler. Political Psychology, https://doi.org/10.1111/pops.12559

Abstract: According to common wisdom, which is supported by extant psychological theorizing, a core feature of political conservatism (vs. liberalism) is the resistance to (vs. acceptance of) societal change. We propose that an empirical examination of the actual difference in political liberals’ and conservatives’ attitudes toward change across different sociopolitical issues may call into question this assumed association between political orientation and relation to change. We examined this proposition in four studies conducted in Germany. In Study 1, we assessed lay people's intuitions about liberals’ and conservatives’ attitudes toward change. Results of this study concur with theoretical assumptions that liberals accept and conservatives resist change. In Study 2a, Study 2b, and Study 3, self‐identified liberals and conservatives were asked whether they would resist or accept change on various sociopolitical issues. Results of these studies suggest that both conservatives and liberals resist and accept societal changes, depending on the extent to which they approve or disapprove of the status quo on a given sociopolitical issue. Overall, our findings provide no evidence for a one‐directional association between political orientation and the tendency to accept or resist change. These findings therefore challenge theoretical and lay assumptions regarding general, context‐independent psychological differences underlying political ideologies.

The most comprehensive genomic analysis of the human brain ever undertaken has revealed new insights into the changes it undergoes through development, how it varies among individuals, and the roots of neuropsychiatric illnesses

Integrative functional genomic analysis of human brain development and neuropsychiatric risks. Mingfeng Li and dozens of authors. Science Dec 14 2018:Vol. 362, Issue 6420, eaat7615. DOI: 10.1126/science.aat7615

Abstract
INTRODUCTION: The brain is responsible for cognition, behavior, and much of what makes us uniquely human. The development of the brain is a highly complex process, and this process is reliant on precise regulation of molecular and cellular events grounded in the spatiotemporal regulation of the transcriptome. Disruption of this regulation can lead to neuropsychiatric disorders.

RATIONALE: The regulatory, epigenomic, and transcriptomic features of the human brain have not been comprehensively compiled across time, regions, or cell types. Understanding the etiology of neuropsychiatric disorders requires knowledge not just of endpoint differences between healthy and diseased brains but also of the developmental and cellular contexts in which these differences arise. Moreover, an emerging body of research indicates that many aspects of the development and physiology of the human brain are not well recapitulated in model organisms, and therefore it is necessary that neuropsychiatric disorders be understood in the broader context of the developing and adult human brain.

RESULTS: Here we describe the generation and analysis of a variety of genomic data modalities at the tissue and single-cell levels, including transcriptome, DNA methylation, and histone modifications across multiple brain regions ranging in age from embryonic development through adulthood. We observed a widespread transcriptomic transition beginning during late fetal development and consisting of sharply decreased regional differences. This reduction coincided with increases in the transcriptional signatures of mature neurons and the expression of genes associated with dendrite development, synapse development, and neuronal activity, all of which were temporally synchronous across neocortical areas, as well as myelination and oligodendrocytes, which were asynchronous. Moreover, genes including MEF2C, SATB2, and TCF4, with genetic associations to multiple brain-related traits and disorders, converged in a small number of modules exhibiting spatial or spatiotemporal specificity.

CONCLUSION: We generated and applied our dataset to document transcriptomic and epigenetic changes across human development and then related those changes to major neuropsychiatric disorders. These data allowed us to identify genes, cell types, gene coexpression modules, and spatiotemporal loci where disease risk might converge, demonstrating the utility of the dataset and providing new insights into human development and disease.


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Press release: In the developing brain, scientists find roots of neuropsychiatric diseases. Bill Hathaway. Yale News, Dec 13 2018. https://news.yale.edu/2018/12/13/developing-brain-scientists-find-roots-neuropsychiatric-diseases

Men in egalitarian tribe hide who are the best hunters, who out of modesty also cooperate masking how successful they are; they all get the girls with equal probability

Foraging Performance, Prosociality, and Kin Presence Do Not Predict Lifetime Reproductive Success in Batek Hunter-Gatherers. Thomas S. Kraft et al. Human Nature, https://doi.org/10.1007/s12110-018-9334-2

Abstract: Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence suggests that status-accruing behaviors such as hunting and prosociality are pathways to reproductive success, but social egalitarianism may diminish this pathway. Here we introduce a mixed longitudinal/cross-sectional dataset based on 45 years of research with the Batek, a population of egalitarian rain forest hunter-gatherers in Peninsular Malaysia, and use it to test the effects of four predictors of lifetime reproductive success: (i) foraging return rate, (ii) sharing proclivity, (iii) cooperative foraging tendency, and (iv) kin presence. We found that none of these factors can explain variation in lifetime reproduction among males or females. We suggest that social egalitarianism, combined with strikingly low infant and juvenile mortality rates, can mediate the pathway between foraging, status-accruing behavior, and reproductive success. Our approach advocates for greater theoretical and empirical attention to quantitative social network measures, female foraging, and fitness outcomes.

Keywords: Hunter-gatherers Reproductive success Foraging Prosociality Sharing Cooperation

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Although Batek took quiet satisfaction in their skills and accomplishments, there was a strong social convention against overt bragging or showing off. Modesty was a valued trait. Hunters with gamewould usually enter camp quietly and then hand the carcass to someone else to butcher and distribute. Gatherers with loads of tubers would distribute their surplus to other families without fanfare. Although Batek strongly guarded their personal autonomy, they also felt an obligation to cooperate with other camp and group members. Competition was suppressed, even in games adopted from outsiders, such as cards.

The most common end-of-life reflections: Concern for loved ones, regret, morbidity and mortality, gratitude, spirituality, legacy, & thoughts about acceptance or non-acceptance of impending death

The most common end-of-life reflections: A survey of hospice and palliative nurses. Michael R. Ent & Mary A. Gergis. Death Studies, https://doi.org/10.1080/07481187.2018.1539053

Abstract: To identify the most common end-of-life reflections among terminally ill patients, 124 nurses from the Hospice and Palliative Nurses Association (HPNA) completed an online, open-ended survey. Common themes of these reflections included concern for loved ones, regret, morbidity and mortality, gratitude, spirituality, legacy, and thoughts about acceptance or non-acceptance of impending death. Nurses reported that their patients were more concerned about their loved ones than their own morbidity and mortality. Common end-of-life reflections may serve as cues that hospice and palliative patients are self-initiating therapeutic life review.

Compliments for women: A metaphor's attractiveness was positively correlated with figurativeness, imageability, romance & arousal but negatively associated with familiarity

Factors contributing to the aesthetic attractiveness of metaphors in a complimentary context. Qi Yang, Zhao Gao, Yang Li. Lingua, https://doi.org/10.1016/j.lingua.2018.10.011

Highlights
•    A metaphor's aesthetic attractiveness is positively correlated with figurativeness, imageability and arousal.
•    Familiarity decreases a metaphor's aesthetic attractiveness.
•    Romance intensified the perception of a metaphor's attractiveness in the context of communication between sexes.

Abstract: Metaphor is widely used in our daily lives to express strong emotions, comprehend abstract concepts and display aesthetic qualities. Women prefer metaphorical language when men pay them compliments in romantic situations; however, in this context, it remains unclear which factors are likely to contribute to the aesthetic attractiveness of metaphor. In the current study, 90 female undergraduates were recruited to rate 477 compliments in terms of language variables (i.e., appropriateness, figurativeness, familiarity, and imageability) and emotional perception (i.e., attractiveness, valence, romance, and arousal) on a 7-point Likert scale. The compliments were generated by 74 men who were required to use language to impress women in a previous independent experiment. A hierarchical regression model was built to explore the potential factors of the aesthetic attractiveness of metaphors. The results showed that a metaphor's attractiveness was positively correlated with figurativeness, imageability, romance and arousal but negatively associated with familiarity, which suggests that metaphors are more attractive when they incorporate high figurativeness, imageability, romance and arousal and low familiarity. Overall, this study indicates that a metaphor's aesthetic attractiveness may be determined by the social context, a communicator's motivation and specific linguistic aspects.

Efficacy of extended clinical management, group CBT, and group plus individual CBT for major depression: Results of a two-year follow-up study

Schaub, Annette & Ulrich, Goldmann & Mueser, Kim & Goerigk, Stephan & Martin, Hautzinger & Elisabeth, Roth & Marketa, Charypar & Rolf, Engel & Hans-Jürgen, Möller. (2018). Efficacy of extended clinical management, group CBT, and group plus individual CBT for major depression: Results of a two-year follow-up study. Journal of Affective Disorders. 238. 10.1016/j.jad.2018.05.081

Objective: Cognitive therapy has gained prominence in the treatment of major depression, however, little is known about its long-term benefits when delivered during inpatient treatment or combined with outpatient treatment with severely ill inpatients (HAM-D > 20).

Method: To evaluate this question, we conducted a randomized controlled trial investigating the efficacy of extended clinical management (E-CM), psychoeducational cognitive behavioural group therapy (PCBT-G) or PCBT-G and 16 outpatient individual treatment sessions (PCBT-G+I). All patients were treated with pharmacotherapy. 177 inpatients with DSM-IV major depression were randomized either to E-CM or PCBT-G or PCBT-G+I. Outcome measures were collected in the hospital at pre- and posttreatment and following discharge into the community every six months for two years. We compared the study groups on symptom changes, psychosocial functioning, knowledge about depression and rehospitalization.

Results: All three treatment interventions are equally effective at reducing depressive symptoms and increasing psychosocial functioning at posttreatment. There was significant group by time interaction for knowledge about depression in favor of PCBT-G and PCBT-G+I over E-CM. We did not find significantly lower rehospitalisation rates at the two-year follow-up for PCBT-G+I compared to E-CM, however, comparing PCBT-G to E-CM.

Conclusions: We conclude that with cognitive psychoeducational group therapy a successful, in the long-term other interventions superior psychological intervention for major depression is available as gains were sustained for two years following discharge from the hospital. More research is needed to evaluate the long-term impact of group treatment starting in inpatient treatment.

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My comment: I do not understand the conclusions...

Sexual selection typically centers on bodily & psychological traits; non-bodily ones (housing, vehicles, art, social media, &c) can, however, influence sexual selection even in absence of the phenotype proper; these are "extended phenotypic traits"

An Updated Theoretical Framework for Human Sexual Selection: from Ecology, Genetics, and Life History to Extended Phenotypes. Severi Luoto. Adaptive Human Behavior and Physiology, https://link.springer.com/article/10.1007%2Fs40750-018-0103-6

Abstract

Objectives: Sexual selection typically centers on bodily and psychological traits. Non-bodily traits ranging from housing and vehicles through art to social media can, however, influence sexual selection even in absence of the phenotype proper. The theoretical framework of human sexual selection is updated in this article by unifying four theoretical approaches and conceptualizing non-bodily traits as extended phenotypic traits.

Methods: Existing research is synthesized with extended phenotype theory, life history theory, and behavioral ecology. To test population-level hypotheses arising from the review, ecological and demographic data on 122 countries are analyzed with multiple linear regression modelling.

Results: A four-factor model of intelligence, adolescent fertility, population density, and atmospheric cold demands predicts 64% of global variation in economic complexity in 1995 and 72% of the variation in 2016.

Conclusions: The evolutionary pathways of extended phenotypes frequently undergo a categorical broadening from providing functional benefits to carrying signalling value. Extended phenotypes require investments in skills and bioenergetic resources, but they can improve survival in high latitudes, facilitate the extraction of resources from the environment, and substantially influence sexual selection outcomes. Bioenergetic investments in extended phenotypes create individual- and population-level tradeoffs with competing life history processes, exemplified here as a global tradeoff between adolescent fertility and economic complexity. The merits of the present model include a more systematic classification of sexual traits, a clearer articulation of their evolutionary-developmental hierarchy, and an analysis of ecological, genetic, and psychological mechanisms that modulate the flow of energy into extended phenotypes and cultural innovations.

Keywords: Economic complexity Evolutionary-developmental psychology Extended phenotype Human behavioral ecology Innovation Intelligence Life history theory Non-bodily ornament Sexual selection Theory unification

Contrary to expectations, we report benefits experienced by some amphibian populations breeding and dwelling in proximity to roads: Better locomotor performance & higher measures of traits related to fitness

Fitter frogs from polluted ponds: the complex impacts of human‐altered environments. Steven P. Brady et al. Evolutionary Applications, https://doi.org/10.1111/eva.12751

Abstract: Human‐modified habitats rarely yield outcomes that are aligned with conservation ideals. Landscapes that are subdivided by roads are no exception, precipitating negative impacts on populations due to fragmentation, pollution, and road kill. Although many populations in human‐modified habitats show evidence for local adaptation, rarely does environmental change yield outright benefits for populations of conservation interest. Contrary to expectations, we report surprising benefits experienced by amphibian populations breeding and dwelling in proximity to roads. We show that roadside populations of the wood frog, Rana sylvatica, exhibit better locomotor performance and higher measures of traits related to fitness compared with frogs from less disturbed environments located further away from roads. These results contrast previous evidence for maladaptation in roadside populations of wood frogs studied elsewhere. Our results indicate that altered habitats might not be unequivocally detrimental, and at times might contribute to metapopulation success. While the frequency of such beneficial outcomes remains unknown, their occurrence underscores the complexity of inferring consequences of environmental change.

The smartphone is the closest device to us, above classmates, colleagues, flatmates; trust & preoccupation mediate the relationship between closeness to the smartphone & stress and coping

Smartphones as digital companions: Characterizing the relationship between users and their phones. Astrid Carolus et al. New Media & Society, https://doi.org/10.1177/1461444818817074

Abstract: Based on the idea of computers constituting social agents and referring to core characteristics of human–human relationships, this study introduces the concept of a digital companionship between smartphone users and their devices. Constituting characteristics (closeness, trust, preoccupation) and outcomes (stress, coping with stress) of social relationships were adapted to yield a model of human–smartphone relationships for empirical testing. A cross-national sample of participants (n = 1156) completed an online study, which included self-report measures as well as a newly developed instrument (Positioning Others and Devices [POD]) assessing the closeness to technical devices and social actors. Results showed the smartphone to be the closest device. Furthermore, structural equation modeling lent support for the theoretical model indicating that trust and preoccupation mediate the relationship between closeness to the smartphone and stress and coping. Findings support the concept of companionship as a fruitful approach to explain smartphone-related behaviors.

Keywords: Digital companion, human–smartphone relationship, mobile devices, relationship, smartphone