Tuesday, August 28, 2018

Autodidactism: We are likelier to grow cranky and conspiracy-minded, mistaking brainstorms for insight while rediscovering what the rest of the world already know

'We Can Read Without Learning at All'.“  Patrick Kurp. Sunday Aug 26 2018.
evidenceanecdotal.blogspot.com/2018/08/we-can-read-without-learning-at-all.html
What we mean by ‘education,’ that strange word, still has mostly to do with books, books we possess, keep.”

[...]

The obvious risk involved in adhering strictly to autodidacticism is waywardness. We require the friction of other minds to buff away self-generated roughness. Few of us can polish ourselves. We are likelier to grow cranky and conspiracy-minded, mistaking brainstorms for insight while rediscovering what the rest of the world already knows. Had I read only the books assigned in class, I would today be only nominally literate. Had I read only the books that confirmed the thoughts I already possessed, I would remain marginally illiterate.

[...]

Fr. Schall reminds us of the thrills and risks of self-education: “We can read without learning at all. We can have read only one book, the Bible or Shakespeare, but read it well. We can read many things, none of which move our souls to attend to what is.”

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The Autodidact Project, by Ralph Dumain: www.autodidactproject.org

Children reproduced outcomes that were positively valued by the experimenter significantly more when he was attentive but were more likely to reproduce negatively valued outcomes when he was inattentive

Botto, Sara Valencia, & Rochat, Philippe. (2018). Sensitivity to the evaluation of others emerges by 24 months. Developmental Psychology, 54(9), 1723-1734. http://dx.doi.org/10.1037/dev0000548

Abstract: Although the human proclivity to engage in impression management and care for reputation is ubiquitous, the question of its developmental outset remains open. In 4 studies, we demonstrate that the sensitivity to the evaluation of others (i.e., evaluative audience perception) is manifest by 24 months. In a first study, 14- to 24-month-old children (N = 49) were tested in situations in which the attention of an audience was systematically manipulated. Results showed that when the experimenter was inattentive, as opposed to attentive, children were more likely to explore an attractive toy. A second study (N = 31) explored whether same-aged children would consider not only the attention of the experimenter but also the values the experimenter expressed for two different outcomes when exploring a toy. We found that children reproduced outcomes that were positively valued by the experimenter significantly more when the experimenter was attentive but were more likely to reproduce negatively valued outcomes when the experimenter was inattentive. A third control study (N = 30) showed that the significant effect of Study 2 disappeared in the absence of different values. Lastly, Study 4 (N = 34) replicated and extended the phenomenon by showing toddler’s propensity to modify their behavior in the presence of 2 different experimenters, depending on both the experimenter’s evaluation of an outcome and their attention. Overall, these data provide the first convergent demonstration of evaluative audience perception in young children that precedes the full-fledged normative, mentalizing, and strong conformity psychology documented in 4- to 5-year-old children.

People reported as less likable, relatable, appealing, and more troublesome female Dark Triad characters, than non-Dark Triad & male characters; Non-Dark Triad males were viewed as more troublesome than non-Dark Triad females

Snyder, G. K., Smith, C. V., Øverup, C. S., Paul, A. L., & Davis, T. M. (2018). Characters we love to hate: Perceptions of dark triad characters in media. Psychology of Popular Media Culture, http://dx.doi.org/10.1037/ppm0000200

Abstract: Although the Dark Triad personality (narcissism, psychopathy, and Machiavellianism) has extensive background research, there has been a lack of investigation into perceptions of people high in the Dark Triad. Using film trailers with prominent Dark Triad characters, the current research examined perceptions of characters in movies and TV shows based on their Dark Triad characteristics and their gender. Undergraduate students (pilot study N = 21; present study N = 86) watched theatrical trailers originally released by the production companies before they rated 2 key characters’ Dark Triad traits with the Dirty Dozen (Jonason & Webster, 2010). Analyses revealed significant interactions such that people reported less positive perceptions (e.g., less likable, relatable, appealing, and more troublesome) of female Dark Triad characters, as opposed to non-Dark Triad characters and male characters. Non-Dark Triad male characters were viewed as more troublesome than non-Dark Triad female characters, and female Dark Triad characters were viewed as the most troublesome. Possible extensions could explore the prevalence and popularity of Dark Triad-type characters in the media and how genders in media have changed over time.

Young women taking and posting “selfies” online: Posting selfies on social media resulted in worsened mood and body image; even posting retouched selfies resulted in harmful effects

“Selfie” harm: Effects on mood and body image in young women. Jennifer S. Mills et al. Body Image, Volume 27, December 2018, Pages 86-92. https://doi.org/10.1016/j.bodyim.2018.08.007

Highlights
•    We examined the behaviour of taking and posting “selfies” online.
•    The current study used an experimental design.
•    Posting selfies on social media resulted in worsened mood and body image.
•    Even posting retouched selfies resulted in harmful effects.

Abstract: “Selfies” (self-taken photos) are a common self-presentation strategy on social media. This study experimentally tested whether taking and posting selfies, with and without photo-retouching, elicits changes to mood and body image among young women. Female undergraduate students (N = 110) were randomly assigned to one of three experimental conditions: taking and uploading either an untouched selfie, taking and posting a preferred and retouched selfie to social media, or a control group. State mood and body image were measured pre- and post-manipulation. As predicted, there was a main effect of experimental condition on changes to mood and feelings of physical attractiveness. Women who took and posted selfies to social media reported feeling more anxious, less confident, and less physically attractive afterwards compared to those in the control group. Harmful effects of selfies were found even when participants could retake and retouch their selfies. This is the first experimental study showing that taking and posting selfies on social media causes adverse psychological effects for women.

Adopting a Stigmatized Label: Social Determinants of Identifying as an Atheist beyond Disbelief

Adopting a Stigmatized Label: Social Determinants of Identifying as an Atheist beyond Disbelief. Christopher P Scheitle, Katie E Corcoran, Erin B Hudnall. Social Forces, Social Forces, soy084, https://doi.org/10.1093/sf/soy084

Abstract: An individual’s identity may not appear to correspond to his or her beliefs and behaviors. Such incongruence may be particularly likely when an identity is stigmatized. We examine this dynamic in the context of atheists. Being an atheist has often been equated with stating a disbelief in God, but this ignores the distinct phenomenon of identifying as an atheist. This study asks what influences the likelihood that an individual will identify as an atheist beyond saying that he or she does not believe in God. Drawing upon research examining the social dynamics of stigma and identity, we hypothesize that having close friends who are atheists will support an individual’s own adoption of the atheist label. On the other hand, we hypothesize that the presence of other stigmatized or at least competing identities, beliefs, and behaviors will serve as a barrier to an individual’s adoption of the atheist label. These expectations are largely supported in an analysis of unique survey data offering separate measures of atheist self-identification and belief in God. This study provides a framework for future research to examine these dynamics in the context of other identities, particularly those that are stigmatized.

Monday, August 27, 2018

Old, from 2017: Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Old, from 2017: Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Ira Espuny-Camacho et al. Neuron, Volume 93, ISSUE 5, P1066-1081.e8 DOI:https://doi.org/10.1016/j.neuron.2017.02.001

Highlights
    Human-mouse chimeric model of Alzheimer’s disease
    PSC-derived human neurons grafted into an AD mouse
    Major degeneration and loss of human neurons in chimeric AD mice
    Absence of tangle pathology in degenerating human neurons in vivo

Summary: Human pluripotent stem cells (PSCs) provide a unique entry to study species-specific aspects of human disorders such as Alzheimer’s disease (AD). However, in vitro culture of neurons deprives them of their natural environment. Here we transplanted human PSC-derived cortical neuronal precursors into the brain of a murine AD model. Human neurons differentiate and integrate into the brain, express 3R/4R Tau splice forms, show abnormal phosphorylation and conformational Tau changes, and undergo neurodegeneration. Remarkably, cell death was dissociated from tangle formation in this natural 3D model of AD. Using genome-wide expression analysis, we observed upregulation of genes involved in myelination and downregulation of genes related to memory and cognition, synaptic transmission, and neuron projection. This novel chimeric model for AD displays human-specific pathological features and allows the analysis of different genetic backgrounds and mutations during the course of the disease.

Until more compelling evidence emerges, however, a propensity to imitate from birth should no longer be considered an established phenomenon

Re-evaluating the neonatal imitation hypothesis. Janine Oostenbroek et al. Developmental Science, DOI: 10.1111/desc.12720

We appreciate Meltzoff et al.’s (2017) detailed commentary on our study of neonatal imitation (Oostenbroek et al., 2016) and the opportunity to clarify critical aspects of the findings. First, however, we wish to highlight that our data were collected as part of a larger longitudinal investigation, in which we set out to examine potential relations between neonatal imitation and later emerging aspects of social cognition (Suddendorf, Oostenbroek, Nielsen, & Slaughter, 2013). Our aim was not to test the veracity of the phenomenon of neonatal imitation, but to assess whether early individual differences predict later imitative and other socio-cognitive capacities, which would support the view of neonatal imitation as the foundation of social cognition (Meltzoff, 2002). When coding was finalized, it became clear that, to our surprise, the data challenged the very existence of the phenomenon whose trajectory and consequences we sought to chart.

Meltzoff et al. (2017) claim that methodological problems biased our results towards null effects. We assert that there is no compelling reason to think that any of these critiques undermine our challenge to the field. For instance, they argue that too many stimuli were used in a within-subjects design, which may have led to neonatal fatigue and disengagement. If that were the case, however, then initial trials should have elicited imitation but not later ones. We found no such order effects in any of our analyses (see Supplementary Material in Oostenbroek et al., 2016). Meltzoff et al. rightly note that infants cannot be expected to imitate behaviors that they are incapable of producing. Our data show, however, that with the exception of the ‘eee’ vocalizations and sad faces, infants produced all target behaviors either occasionally or regularly. [...]

The literature on neonatal imitation has a long history of post-hoc theorizing. In response to early failures to replicate the effect, for example, it was stipulated that neonates should be unfamiliar with the model’s face to maintain interest during the experiment (Meltzoff & Moore, 1983a). Later, however, it was argued that infants imitate familiar faces to communicate recognition (Meltzoff, 2005; Meltzoff & Moore, 1994), and that ‘imitation is not modified by which person serves as the model’ (Meltzoff & Moore, 1992, p. 492). Now, Meltzoff et al. again argue that the model should be unfamiliar, even suggesting that this is the ‘key’ to eliciting neonatal imitation. Setting aside the obvious contradictions here, it seems untenable to claim that the ‘engine and mechanism for the growth of social cognition’ (Meltzoff, 2002, p. 7) would manifest itself only with unfamiliar people.

Individuals with stronger social anxiety perceive their environment as hierarchically organized & their own position relatively low; positive evaluations might mean problems, so a goal could be protection by avoiding making “too good” of an impression

Malaise with praise: A narrative review of 10 years of research on the concept of Fear of Positive Evaluation in social anxiety. Julia Reichenberger, Jens Blechert. Depression and Anxiety, https://doi.org/10.1002/da.22808

Abstract: Social anxiety is characterized by a fear of being negatively evaluated by others (i.e., Fear of Negative Evaluation [FNE]). In 2008, Weeks, Heimberg, and Rodebaugh proposed Fear of Positive Evaluation (FPE) as a second cognitive component in social anxiety. The article presents an overview of FPE, its psycho‐evolutionary theoretical foundation and assessment by the Fear of Positive Evaluation Scale as well as relevant psychometric research on demographic characteristics. The relationship of FPE with a wide range of established dimensions from clinical, personality, and social psychology (i.e., self‐esteem, perfectionism, or quality of life) will be reviewed. The role of FPE for psychological comorbidities such as other anxiety disorders, depression, eating, and substance use disorders as well as for treatment of social anxiety will be discussed. Future research might address questions of causality of FPE relative to related constructs, further data on psychometric properties, as well as on its independence from FNE in longitudinal studies. In sum, FPE seems to be a valid and reliable construct that explains cognitions, emotions, and behavior related to social anxiety at subclinical and clinical levels and therefore enriches the psychometric repertoire in the fields of social psychology, personality, and clinical psychology.


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A theoretical framework for FPE stems from the psycho-evolutionary model of social anxiety by Gilbert (2001, 2014) and was adapted by Weeks et al. (2008a). Accordingly, individuals with stronger social anxiety perceive their environment as hierarchically organized, and see their own position in the hierarchy as relatively low. Their ultimate goal is supposedly a stable, intermediate position and an avoidance of upward or downward shifts in the social hierarchy. This “inconspicuous” intermediate position is the result of two “regulatory forces”, FNE and FPE (see Figure 1). Specifically, the upward movements in the social hierarchy, implied in positive evaluation, might attract the group's attention, prompting higher-ranking group members to compete and challenge this new “rising star.” Hence, the goal of FPE could be protection from this threat by avoiding making “too good” of an impression, thereby avoiding an upward shift in social hierarchy.

Pink for Girls, Red for Boys, and Blue for Both Genders: Colour Preferences in Children and Adults

Pink for Girls, Red for Boys, and Blue for Both Genders: Colour Preferences in Children and Adults, Domicele Jonauskaite et al. Sex Roles, https://link.springer.com/article/10.1007/s11199-018-0955-z

Abstract: Colours carry social connotations like pink for girls and blue for boys. In a cross-sectional study, we investigated whether such early gender coding might be reflected in absolute colour preferences in children and adults of both genders. In two studies, participants selected their favourite (and least favourite, Study 2) colour from an unrestricted sample of colours. We tested 129 Swiss children (Study 1, 10–14 years-old, 68 boys) and 180 Swiss adults (Study 2, 17–48 years-old, 88 men). In children, we observed that girls chose pink/purple as their favourite hue more often than boys did, the most common favourite hue in girls and boys was blue, and boys chose red as their favourite more often than girls did. In adults, we observed that both genders almost never choose pink as their favourite, blue was a common favourite colour, and women were more likely to favour red than were men. In an additional study (n = 183 Swiss participants, 47 men), we tested whether liking of pink, blue, and red was related to emotion associations with these colours. Pink was associated with positive emotions to the same extent as blue and red. Women further associated more positive emotions with pink than did men. We conclude that some commonalities (blue) and gender differences (pink and red) exist in absolute colour preferences. These differences, however, cannot be fully accounted by emotional associations. We speculate about these gendered colour preferences in relation to gender stereotypes and status differences between men and women.

American adolescents positive trends in four areas: substance use, unprotected sex, crime, & hazardous driving; possible causes are the effects of public policies, closer parent–child relationships, & the social consequences of electronic media use

Arnett, J. J. (2018). Getting better all the time: Trends in risk behavior among American adolescents since 1990. Archives of Scientific Psychology, 6(1), 87-95. http://dx.doi.org/10.1037/arc0000046

Abstract: Contrary to the negative narrative in psychology and in the American public, many trends in the risk behaviors of American adolescents have been positive in recent decades. Evidence is presented for positive trends in four areas: substance use, unprotected sex, crime, and hazardous automobile driving. A comparison of American adolescents to older Americans and to adolescents in other developed countries indicates that the pattern of positive trends is distinct to young Americans and does not apply consistently across age groups and countries. Three explanations for the positive trends are considered: the effects of public policies, closer parent–child relationships, and the social consequences of electronic media use. The most promising hypothesis is that a rise in electronic media use led to a decline in unstructured socializing, which led in turn to lower risk behavior.

Impact Statement: Contrary to the negative narrative in psychology and in the American public, many trends in the risk behaviors of American adolescents have been positive in recent decades. Evidence is presented for positive trends in four areas: substance use, unprotected sex, crime, and hazardous automobile driving. A comparison of American adolescents to older Americans and to adolescents in other developed countries indicates that the pattern of positive trends is distinct to young Americans and does not apply consistently across age groups and countries. Three explanations for the positive trends are considered: the effects of public policies, closer parent–child relationships, and the social consequences of electronic media use. The most promising hypothesis is that a rise in electronic media use led to a decline in unstructured socializing, which led in turn to lower risk behavior.



Saturday, August 25, 2018

Milgram replication: In conditions where the participants were not given money up front it was necessary to employ more verbal prompts in order to induce obedience

The (doubtful) role of financial reward in obedience to authority. Dariusz Dolinski & Tomasz Grzyb. The Journal of Social Psychology, https://doi.org/10.1080/00224545.2018.1505708

ABSTRACT: The Milgram experiments are among the most well-known and important in the history of psychology. Since first published, there have been countless discussions held on the subject of what factors induce people to exhibit extreme obedience towards authority. One such potential factor, not yet explored empirically, is the receipt in advance of financial gratification by a study participant. In our experiment we compare obedience among participants in classic Milgram paradigm conditions with obedience in a situation where the participant does not receive financial gratification in advance. The results did not show that obedience differed in the two comparable situations. In conditions where the participants were not given money up front, however, it was necessary to employ more verbal prompts in order to induce obedience.

Keywords: Obedience, financial gratification, reciprocity

Women are usually somewhat earlier chronotypes, who go to bed earlier, fall asleep earlier, and then get up a little earlier; this difference arises with puberty and ends with menopause, from which a reproductive function can be interpreted

The chronotype in relationships and sexual behavior - a first overview (automatic translation of Der Chronotyp in Beziehungen und Sexualverhalten – eine erste Übersicht). Christoph Randler. Somnologie, https://link.springer.com/article/10.1007/s11818-018-0176-2

Abstract: A late chronotype (owls) is someone who tends to go to bed late, so he or she will get up later. In contrast, morning types (larks) get up earlier and go to bed earlier. Men and women differ in their chronotype. Women are usually somewhat earlier chronotypes, who go to bed earlier, fall asleep earlier, and then get up a little earlier. Interestingly, this difference arises with puberty and ends with menopause, from which a reproductive function can be interpreted. From an evolutionary Darwinian perspective, this is a sexual dimorphism that can be explained by sexual selection. Various studies have indeed shown that men of the evening type reported more sexual partners, in Italy, Sri Lanka and Germany. Furthermore, studies show that assortative behaviour takes place when choosing a partner, i. e. there are more couples whose partners are similar the chronotype. However, there are still many open questions related to this topic.

On the positive association between candy and fruit gum consumption and hyperactivity in children and adolescents with ADHD

On the positive association between candy and fruit gum consumption and hyperactivity in children and adolescents with ADHD. Nicole Wolff et al. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. https://doi.org/10.1024/1422-4917/a000609

Abstract

Objective: The purpose of the present study was the analysis of the association between consumption of candy and fruit gums, diagnosis of attention deficit hyperactivity disorder (ADHD), and behavioural problems.

Methods: In total, 1,187 children and adolescents of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) were analyzed. Results: It was observed that children and adolescents with ADHD as compared to healthy controls (HC) reported to consume more frequently and higher amounts of candy and fruit gums and that hyperactivity was associated with frequent candy and fruit gum consumption.

Conclusions: Because with the present design no conclusions on causality or directionality of the found associations could be drawn, results are discussed quite broadly in the light of several previously published interpretations, also to serve as a generator for further research. One more innovative speculation is that children and adolescents with ADHD may consume more frequently candy and fruit gums in order i) to compensate for their higher needs of energy resulting from hyperactive behaviour and/or ii) to compensate for the ADHD-typical deficits in the “reward cascade”.

Keywords: ADHD, nutrition, hyperactivity, children, adolescents

Weak positive correlation for psychopathic tendencies & leadership emergence, weak negative association with leadership effectiveness, & moderate negative correlation with transformational leadership

Shall We Serve the Dark Lords? A Meta-Analytic Review of Psychopathy and Leadership. Karen Landay, Peter D Harms, Marcus Credé. https://www.researchgate.net/publication/327039686

Abstract: Both scholars and the popular press have expressed concern regarding the potential prevalence of individuals with psychopathic tendencies in corporate leadership positions and the negative effects they may have on both individual workers and their organizations as a whole. However, research to date has been inconclusive as to whether such individuals are more likely to emerge as leaders or if they are (in)effective leaders. In order to clarify the state of the literature, we conducted a meta-analysis on the association between psychopathic personality characteristics and leadership emergence, leadership effectiveness, and transformational leadership. Our results, based on data from 92 independent samples, showed a weak positive correlation for psychopathic tendencies and leadership emergence, a weak negative association for psychopathic tendencies and leadership effectiveness, and a moderate negative correlation for psychopathic tendencies and transformational leadership. Subgroup analyses on methodological factors did not indicate any differences from the main results. However, moderator analyses showed a gender difference in these associations such that psychopathic tendencies in men were weakly positively correlated with leadership emergence and effectiveness and negatively correlated with transformational leadership, while psychopathic tendencies in women were negatively associated with effectiveness and transformational leadership, and largely unassociated with emergence. Additionally, small but consistent curvilinear associations were found for all leadership criteria. Overall, these results suggest that concern over psychopathic tendencies in organizational leaders may be overblown, but that gender can function to obscure real effects.

Increases in Sex with Same-sex Partners Across U.S. Cohorts Born 1920-1998

Mishel, Emma, Paula England, Jessie Ford, and Monica Caudillo. 2018. “Increases in Sex with Same-sex Partners Across U.S. Cohorts Born 1920-1998: A Race-gender Intersection.” SocArXiv. August 24. doi:10.31235/osf.io/af8qk

Abstract: We examine change across U.S. cohorts born between 1920 and 1998 in their probability of having had sex with same-sex partners last year and since age 18. We explore how trends differ by gender, race and class background. We use data from the 1988-2016 General Social Surveys. We find steady increases across birth cohorts in the proportion of men and women who have had both male and female sexual partners since age 18. A key finding is a race-gender intersection: black men and women of all races had similar increases— increases which were much steeper than those observed for white men. We suggest that women’s increase is rooted in a long-term asymmetry in gender change, in which nonconformity to gender norms in many arenas is more acceptable for women than men. As the increase for men is largest among black men—and this is the population most affected by the rise of mass incarceration—we suggest the latter may be a contributing factor.

Pleasantness was induced by mere imagination of touch without any tactile stimulation, & touch that was sexually arousing for the receiver was rated as more sexually arousing for the giver as well, pointing to top-down, learned expectations of sensory pleasure and erogeneity

Dissociable sources of erogeneity in social touch: Imagining and perceiving C-Tactile optimal touch in erogenous zones. Elena Panagiotopoulou, Maria Laura Filippetti, Antje Gentsch, Aikaterini Fotopoulou. PLOS One, https://doi.org/10.1371/journal.pone.0203039

Abstract: Previous research points to two major hypotheses regarding the mechanisms by which touch can be experienced as erotogenic. The first concerns the body part to which touch is applied (erogenous zones) and the second the modality of touch (sensual touch optimal in activating C Tactile afferents). In this study, we explored for the first time the relation between those two mechanisms in actual and imagined social touch. In a first experiment, we randomly assigned “Giver” and “Receiver” roles within 19 romantic couples (20 females, 18 males, age 32.34 ± 8.71SD years) and asked the “Giver” to apply CT-optimal (3 cm/s) vs. CT-suboptimal (18 cm/s) touch on an erogenous (neck) vs. non-erogenous zone (forehead) of their partner. We then obtained ratings of pleasantness and sexual arousal from both “Receivers” and “Givers”. In a second experiment, 32 healthy females (age 25.16 ± 5.91SD years) were asked to imagine CT-optimal vs. CT-suboptimal stimulation (stroking vs. patting) and velocity (3 cm/s vs. 18 cm/s) on different erogenous vs. non-erogenous zones and rate pleasantness. While both erogenous body part and CT-optimal, sensual touch were found to increase pleasant and erotic sensations, the results showed a lack of an interaction. Furthermore, Pleasantness was induced by mere imagination of touch without any tactile stimulation, and touch that was sexually arousing for the receiver was rated as more sexually arousing for the giver as well, pointing to top-down, learned expectations of sensory pleasure and erogeneity. Taken together, these studies provide the first direct evidence that while both the body location to which touch is applied and the mode of touch contribute to pleasant and erotic sensations, these two factors appear to mediate subjective pleasantness and erogeneity by, at least partly, independent mechanisms.

Friday, August 24, 2018

Effects of a Hypnosis Session Before General Anesthesia on Postoperative Outcomes in Patients Who Underwent Minor Breast Cancer Surgery

Effects of a Hypnosis Session Before General Anesthesia on Postoperative Outcomes in Patients Who Underwent Minor Breast Cancer Surgery - The HYPNOSEIN Randomized Clinical Trial. Jibba Amraoui et al. JAMA Network Open. 2018;1(4):e181164. doi:10.1001/jamanetworkopen.2018.1164

Key Points

Question  What is the benefit of a short hypnosis session before general anesthesia on postoperative outcomes (pain, nausea/vomiting, fatigue, comfort/well-being, anxiety, postanesthesia care unit length of stay, and patient satisfaction) in patients who underwent minor breast cancer surgery?

Findings  In this randomized clinical trial, 150 women were randomized to receive hypnosis or a control group, and the mean breast pain score before discharge was 1.75 in the control arm vs 2.63 in the hypnosis arm. At discharge, no statistically significant difference in breast pain was reported.

Meaning  No benefit of hypnosis was found on postoperative breast pain; however, hypnosis seems to have other benefits regarding fatigue, anxiety, and patient satisfaction.

Abstract

Importance  Hypnosis is now widespread in medical practice and is emerging as an alternative technique for pain management and anxiety. However, its effects on postoperative outcomes remain unclear.

Objective  To evaluate the efficacy of a preoperative hypnosis session for reducing postoperative breast pain in patients who underwent minor breast cancer surgery.

Design, Setting, and Participants  The HYPNOSEIN prospective randomized clinical trial was conducted from October 7, 2014, to April 5, 2016. In this multicenter study in France, 150 women scheduled for minor breast cancer surgery were randomized between control and hypnosis arms, and 148 (71 control and 77 hypnosis) were included in the intent-to-treat analysis.

Intervention  On the day of surgery, eligible patients were randomly assigned (1:1) to the control arm or the hypnosis arm. Patients (but not the care teams) were blinded to the arm to which they were assigned. A 15-minute hypnosis session before general anesthesia in the operating room was performed in the hypnosis arm.

Main Outcomes and Measures  The primary end point was breast pain reduction (by 2 on a visual analog scale), assessed immediately before discharge from the postanesthesia care unit (PACU). Secondary end points were nausea/vomiting, fatigue, comfort/well-being, anxiety, and PACU length of stay, assessed at different times until postoperative day 30.

Results  The median patient age was 57 years (range, 33-79 years) in the control arm and 53 years (range, 20-84 years) in the hypnosis arm. Baseline characteristics were similar in the 2 arms. The median duration of the hypnosis session was 6 minutes (range, 2-15 minutes). The use of intraoperative opioids and hypnotics was lower in the hypnosis arm. The mean (SD) breast pain score (range, 0-10) was 1.75 (1.59) in the control arm vs 2.63 (1.62) in the hypnosis arm (P = .004). At PACU discharge and with longer follow-up, no statistically significant difference in breast pain was reported. Fatigue was significantly lower in the hypnosis arm on the evening of surgery (mean [SD] score, 3.81 [2.15] in the control arm vs 2.99 [2.56] in the hypnosis arm; P = .03). The median PACU length of stay was 60 minutes (range, 20-290 minutes) in the control arm vs 46 minutes (range, 5-100 minutes) in the hypnosis arm (P = .002). Exploratory analyses according to patient perception of whether she received hypnosis showed significantly lower fatigue scores in the perceived hypnosis subgroup on the evening of surgery (mean [SD], 4.13 [2.26] for no perceived hypnosis vs 2.97 [2.42] for perceived hypnosis; P = .01). Anxiety was also significantly lower on the evening of surgery in the perceived hypnosis subgroup (mean [SD], 0.75 [1.64] for perceived hypnosis vs 1.67 [2.29] for no perceived hypnosis; P = .03).

Conclusions and Relevance  The results of this study do not support a benefit of hypnosis on postoperative breast pain in women undergoing minor breast cancer surgery. However, other outcomes seem to be improved, which needs to be confirmed by further studies.

Higher early adulthood cognitive ability was associated with more frequent alcohol consumption & binge drinking in midlife; the relation did not change to a large degree when further adjusted for education, & if any resulted in a stronger association

The interplay between cognitive ability, alcohol consumption, and health characteristics. E. Degerud et al. Psychological Medicine, Volume 48, Issue 12, September 2018, pp. 2011-2022. https://doi.org/10.1017/S0033291717003543

Abstract

Background: Higher cognitive ability is associated with favourable health characteristics. The relation between ability and alcohol consumption, and their interplay with other health characteristics, is unclear. We aimed to assess the relationship between cognitive ability and alcohol consumption and to assess whether alcohol consumption relates differently to health characteristics across strata of ability.

Methods: For 63 120 Norwegian males, data on cognitive ability in early adulthood were linked to midlife data on alcohol consumption frequency (times per month, 0–30) and other health characteristics, including cardiovascular risk factors and mental distress. Relations were assessed using linear regression and reported as unstandardised beta coefficients [95% confidence interval (CI)].

Results: The mean ± s.d. frequency of total alcohol consumption in the sample was 4.0 ± 3.8 times per month. In the low, medium, and high group of ability, the frequencies were 3.0 ± 3.3, 3.7 ± 3.5, and 4.7 ± 4.1, respectively. In the full sample, alcohol consumption was associated with physical activity, heart rate, fat mass, smoking, and mental distress. Most notably, each additional day of consumption was associated with a 0.54% (0.44–0.64) and 0.14% (0.09–0.18) increase in the probability of current smoking and mental distress, respectively. In each strata of ability (low, medium, high), estimates were 0.87% (0.57–1.17), 0.48% (0.31–0.66) and 0.49% (0.36–0.62) for current smoking, and 0.44% (0.28–0.60), 0.10% (0.02–0.18), and 0.09% (0.03–0.15) for mental distress, respectively.

Conclusions: Participants with low cognitive ability drink less frequently, but in this group, more frequent alcohol consumption is more strongly associated with adverse health characteristics.

Mindfulness makes one more aware of present and incoming information & is relevant to food choice and food sustainability issues; it may increase disgust & reduce attitudes toward eating insects

Mindfulness and Willingness to Try Insects as Food: The Role of Disgust. Eugene Y. Chan. Food Quality and Preference, https://doi.org/10.1016/j.foodqual.2018.08.014

Highlights
•    Mindfulness makes one more aware of present and incoming information.
•    Mindfulness is relevant to food choice and food sustainability issues.
•    We study and test the impact of mindfulness on insect-eating attitudes.
•    Mindfulness may increase disgust and reduce attitudes toward eating bugs.
•    Results from three studies are consistent with this theorizing.

Abstract: Mindfulness, commonly associated with Buddhism, refers to the state of being aware, taking note of what is going on within oneself and outside of the world. In the current research, we examine the possible impact of mindfulness on willingness to try insect foods. We present the results of three studies—one correlational and two experimental—illustrating that mindfulness increases disgust and lowers willingness to try eating insects. On the one hand, this counters existing literature that mindfulness reduces emotional reactivity. On the other hand, it is in-line with mindfulness making one more aware and accepting of present and incoming information, which would conceivably include context-relevant emotions such as disgust in the case of eating insects that Western cultures see as disgusting. Our findings support the latter possibility. We situate our work within the literature on the various impacts of mindfulness on food choice. We also discuss implications for food sustainability practitioners.

Thursday, August 23, 2018

The Evolution of Human Female Sexual Orientation

The Evolution of Human Female Sexual Orientation. Austin John Jeffery et al. [in press, Evolutionary Psychological Science, July 2018]. http://toddkshackelford.com/downloads/Jeffery-et-al-EPS.pdf

Abstract: Female sexual orientation has received less theoretical and empirical attention than male sexual orientation and few reviews are devoted to female sexual orientation. Moreover, research investigating female sexual orientation often underappreciates insights afforded by evolutionary theory. This review begins with an overview of the literature on female sexual identification, sexual perception, sexual fluidity, sexual expression, and the biology of female sexual orientation. Female same-sex sexual behaviors in the non-human apes are then described, providing a comparative context for the following discussion of hypotheses for the evolution of human female same-sex sexual attractions and behaviors. These hypotheses are organized as byproduct hypotheses or adaptation hypotheses and we include discussions of dysfunction, heterosis, sexual antagonism, epigenetics, weak selection, self-domestication, sexual frustration, mate attraction, alloparenting, polygyny, and other topics. We conclude by highlighting the challenges posed by evolutionary studies of human psychology.

Keywords: evolution, female homosexuality, female sexuality, sexual orientation

Introduction of a machine translation system has significantly increased international trade on eBay, increasing exports by 17.5%; heterogeneous treatment effects are all consistent with a substantial reduction in translation-related search costs

Does Machine Translation Affect International Trade? Evidence from a Large Digital Platform. Erik Brynjolfsson, Xiang Hui, Meng Liu. NBER Working Paper No. 24917, Aug 2018. www.nber.org/papers/w24917

Abstract: Artificial intelligence (AI) is surpassing human performance in a growing number of domains. However, there is limited evidence of its economic effects. Using data from a digital platform, we study a key application of AI: machine translation. We find that the introduction of a machine translation system has significantly increased international trade on this platform, increasing exports by 17.5%. Furthermore, heterogeneous treatment effects are all consistent with a substantial reduction in translation-related search costs. Our results provide causal evidence that language barriers significantly hinder trade and that AI has already begun to improve economic efficiency in at least one domain.

Physically attractive women had more intelligent husbands; a man's physical attractiveness was not associated with his wife’s intelligence; the results provide new information on cross-trait assortative mating

Cross-Trait Assortment for Intelligence and Physical Attractiveness. Curtis S. Dunkel et al. In press, Evolutionary Behavioral Sciences, July 2018. http://toddkshackelford.com/downloads/Dunkel-et-al-EBS.pdf

Abstract: We investigated cross-trait assortative mating for the traits of physical attractiveness and intelligence using data from the Wisconsin Longitudinal Study. It was hypothesized that more physically attractive individuals would have a spouse that was more intelligent, but that this association would be moderated by sex. Specifically, we predicted that more physically attractive women would have more intelligent husbands, but that a man’s physical attractiveness would not predict his wife’s intelligence. The results of correlation and regression analyses were consistent with these predictions, although the effect sizes were small. Additionally, we identified an interaction in which women’s physical attractiveness was more strongly associated with their husbands’ intelligence for more intelligent women than for less intelligent women. We conclude with suggestions for further research addressing cross-trait assortative mating for physical attractiveness and intelligence.

Exploring the Relationship Between Depression and Dementia

Exploring the Relationship Between Depression and Dementia. Rita Rubin. JAMA. Published online August 22, 2018. doi:10.1001/jama.2018.11154

Diagnosing and treating depression in people with mild cognitive impairment (MCI) or with dementia presents special challenges, but doing so can improve the quality of their lives as well as the lives of their caregivers and, in the case of MCI, might even delay progression to dementia.
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Researchers are still trying to tease out the relationship between depression and dementia. While depression does not appear to cause dementia, it likely is a risk factor, just as dementia is a risk factor for depression, said George Alexopoulos, MD, founder and director of the Weill-Cornell Institute of Geriatric Psychiatry. At least 20% of people with dementia develop a depressive syndrome, Alexopoulos said.

Often, though, the depression comes first. Some studies suggest that depression in early life is a risk factor for dementia, while depression later in life can be a prodrome of dementia, Alexopoulos said. Although findings are mixed, a 2014 review of the literature concluded that there is convincing evidence to suggest that depression can be a risk factor and a prodromal symptom of dementia.

In a more recent large longitudinal cohort study published in 2017 in JAMA Psychiatry, researchers followed the trajectory of depressive symptoms and dementia in 10 189 UK men and women over 28 years. Unlike some previous studies, this one found that depressive symptoms in midlife, even if chronic or recurring, were not associated with an increased risk of dementia. However, participants with depressive symptoms later in life had a higher risk of dementia. Depressive symptoms appear to be a prodromal feature of dementia or, perhaps, share common causes, such as neurodegeneration and inflammation, but they do not appear to increase the risk of dementia, according to the authors.

In contrast, another longitudinal study involving 4992 older Australian men, published 2 months earlier, found that those who had a history of depression earlier in life did have a higher risk of dementia than those who did not. However, the association was greater in men who were depressed when they entered the study. Treatment with antidepressants did not decrease the risk of depression-associated dementia, leading the authors to conclude that late-life depression should be considered an early sign of dementia, not a modifiable risk factor.

“Any time you have the first episode (of depression) at a later age, that’s always concerning for a neurodegenerative disorder,” said Anna Burke, MD, a geriatric psychiatrist and the director of neuropsychiatry at Barrow Neurological Institute in Phoenix, who was not involved with either study.

Raj Shah, MD, an associate professor of family medicine with the Rush University Alzheimer Disease Center in Chicago, recommends that a first episode of depression in older individuals be considered a sentinel event, the same way a fall is. Both events should spur questions about whether patients need to have their medication adjusted or whether the fall or the mood change is a marker of other conditions, Shah said.

Difficult Diagnosis

Depression is often overlooked when it accompanies dementia, Burke said.

“The problem is the DSM-5 [Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition)] criteria we use for major depressive disorder don’t necessarily fit for this population, much like in children, where depression presents differently,” she said.

As with children, adults living with dementia and depression might not talk about emotional pain or feeling down, Burke said. Instead, they might exhibit irritability—“they may just get a little more feisty,” she said—and an increase in somatic symptoms, such as aches and pains and gastrointestinal complaints.

“Sometimes people don’t get diagnosed with depression because there is such a huge overlap in symptoms between depression and dementia as well as growing older,” Burke said. Symptoms common to both depression and dementia include loss of interest in activities and hobbies, social withdrawal, and impaired thinking.

Because the symptoms overlap, caregivers might not recognize depression in people with dementia. “I’m often the first person to bring it up,” Burke said. “Even when people do seek treatment in the community, many physicians are not focused on treating anything beyond the memory changes. Nobody ever really discusses the behavioral changes, the changes in mood.”

Still, Alexopoulos said, “If you see the patient at the wrong time, you may miss it. Patients with dementia underreport depression, and caregivers are unreliable reporters.”

As David Steffens, MD, MHS, explained, “It’s hard to notice a change in mood when somebody can’t really voice how they’re feeling.”

But that doesn’t mean depression is insignificant in the setting of dementia. “One reason to treat depression is that depression makes underlying cognitive impairment much worse,” said Steffens, chairman of psychiatry at the University of Connecticut. “You want to give them their best cognitive chance.” Besides antidepressants, he said, psychiatrists have sometimes used electroconvulsive therapy to treat severe depression in people with mild dementia.

Drug Therapy

The prescribing of antidepressants to people with dementia appears to be increasing, according to a UK study published in 2017. Trends in diagnosis and treatment of people with dementia suggest that the proportion prescribed antidepressants rose from 28% to 36.6% from 2005 to 2015.

Antidepressants don’t seem to work as well in people with dementia, possibly because “depression in dementia is a different illness” than depression in people with normal cognition, Alexopoulos said. Cognitive control dysfunction in dementia appears to decrease the effectiveness of some selective serotonin reuptake inhibitors (SSRIs), he and his coauthors wrote in a 2015 article. “I think it is appropriate to try to treat with as little medication as you can,” in part because polypharmacy can lead to delirium syndromes in patients with dementia, Alexopoulos said.

Although the study of Australian men found that taking antidepressants did not reduce the risk of depression-associated dementia, recent research suggests that the drugs might slow the progression to dementia in people with MCI and depression. That study, published in 2017, found that taking the antidepressant citalopram (Celexa), an SSRI, for more than 4 years was associated with a delay in progression from MCI to Alzheimer disease by about 3 years. “Three years is a big deal in this age group,” Alexopoulos said. Experiments in mice and healthy humans have shown that citalopram reduces amyloid plaque, one of the hallmarks of Alzheimer disease.

Treating depression in people with MCI with antidepressants might slow the progression to dementia, but little is known about whether drugs and other interventions developed to treat Alzheimer disease have any effect on depression.

Most clinical trials of potential Alzheimer disease treatments do not consider neuropsychiatric symptoms such as depression or irritability as primary research targets, even though “these symptoms are widely recognized as the most stressful and challenging manifestations of dementia,” concluded authors of a recent review article. Only 17.7% of the relevant studies they found on clinicaltrials.gov tested the effect of pharmacological or nonpharmacological interventions on neuropsychiatric symptoms, they wrote.

Beyond Medication and Talk Therapy

People with MCI might still be able to benefit from cognitive behavioral therapy or psychotherapy, but that becomes less likely as they decline, Burke said. “A huge part of psychotherapy is being able to remember what happened in a session.”

Even individuals whose dementia is too advanced for talk therapy can still benefit from lifestyle changes, though, Burke said. Engaging them in social activities and modifying their environment to minimize triggers that make them anxious or irritable can help improve their quality of life, she said.

A recent pilot study suggested that increasing exposure to daylight can reduce depression in people with dementia. The 12-week study involved 77 people living in 8 dementia care communities. At 4 of the communities, staff took study participants to a room with windows for socialization from 8 am to 10 am each day. At the other 4 communities, staff took study participants to socialize in the mornings in a room illuminated only with typical artificial light.

At the end of the study, participants who had socialized in the rooms with daylight had a statistically significant decrease in their scores on the Cornell Scale for Depression in Dementia, while the other participants did not. More studies are needed to determine the appropriate timing, duration, wavelength, and intensity of light exposure for adults with dementia, the researchers concluded.

Another recent study suggested a perceived lack of social engagement is also associated with depressive symptoms in people with dementia. Researchers measured social engagement, medication use, and depressive symptoms in 402 community-dwelling adults whose average age was 86 years. The data were collected during the first interview at which the participants met the criteria for a dementia diagnosis. The researchers found a link between perceived social isolation and the severity of depressive symptoms but not between antidepressant use and severity of depressive symptoms.

Because the study participants were newly diagnosed, their dementia was mild to moderate. “At that stage, people can still engage,” coauthor Shah said. “If we break down some of the stigma around the diagnosis of dementia, it will help people build cultures of support and inclusiveness.”

We assigned endowments to individuals who could spend all or part of those endowments on a charitable donation; consistent with our hypothesis, subjects may engage in charitable giving to signal their smarts

Giving to Charity to Signal Smarts Evidence from a Lab Experiment. Felipe Montano, Ricardo Perez-Truglia. Journal of Behavioral and Experimental Economics, https://doi.org/10.1016/j.socec.2018.08.004

Highlights
•    We propose individuals give to charity to signal smarts.
•    We designed a laboratory experiment to test this hypothesis.
•    Individuals have to donate out of an endowment.
•    We randomize the publicity of the donation.
•    We randomize if the endowments are distributed at random or according to intelligence.
•    We find suggestive evidence that donations are used to signal smarts.

Abstract: The literature on charitable giving suggests that individuals may use their charitable donations to signal their altruism or their income. We argue that, rather than signaling income per se, individuals may want to signal other unobservable characteristics that correlate to income, such as their intelligence. We designed a laboratory experiment to test this hypothesis. We assigned endowments to individuals who could spend all or part of those endowments on a charitable donation. We cross-randomized the visibility of donations and the individuals’ perceptions about the effect of intelligence on the allocation of endowments. We found that the effect of donation visibility on donation amounts depends sharply on whether the individuals perceive that endowments are determined by intelligence. This evidence suggests that, consistent with our hypothesis, subjects may engage in charitable giving to signal their smarts.